Wales coach Warren Gatland has dropped centres Nick Tompkins and George North as part of four changes to the side that will face France in the Six Nations on Sunday.
Captain Dafydd Jenkins has been moved from the second row to flanker as a new centre partnership of Joe Roberts and Owen Watkin takes over North and Tompkins, who have 155 caps between them.
It will be Llanelli centre Roberts’ first Six Nations start after making his Test debut against England last summer in a World Cup warm-up match.
Elsewhere, Will Rowlands has been called up as Adam Beard’s second-row partner, while hooker Ryan Elias replaces Elliot Dee.
“There are a few changes to the team this week as there are some players that deserve an opportunity,” said Gatland.
“It will be a tough, physical challenge from France on Sunday, particularly up front. We know they will start hard, and it is about us staying in the fight, having good line speed defensively and keeping our discipline.
“We are looking for an 80-minute performance. We are excited to be back at home for our last two matches and looking
forward to getting out in front of a passionate Welsh crowd.”
Wales have lost the last four Six Nations games against France, but they tackle a struggling Les Bleus team that lost to Ireland and drew at home against Italy either side of narrowly beating Scotland.
However, Wales are yet to win in this season’s tournament ahead of their final two fixtures against France and Italy.
Wales are yet to win in this year’s Six Nations
Wales: 15 Cameron Winnett, 14 Josh Adams, 13 Joe Roberts, 12 Owen Watkin, 11 Rio Dyer, 10 Sam Costelow, 9 Tomos Williams; 1 Gareth Thomas, 2 Ryan Elias, 3 Keiron Assiratti, 4 Will Rowlands, 5 Adam Beard, 6 Dafydd Jenkins (c), 7 Tommy Reffell, 8 Aaron Wainwright.
Replacements: 16 Elliot Dee, 17 Corey Domachowski, 18 Dillon Lewis, 19 Alex Mann, 20 Mackenzie Martin, 21 Gareth Davies, 22 Ioan Lloyd, 23 Mason Grady.